The Diagnosis of Insulinoma and Tumor Localization
Jun Zhu
Abstract
Jun Zhu
Abstract
Objective To evaluate the diagnosis of insulinoma and tumor localization in 4 cases.Methods There were 4 patients diagnosed as insulinoma in our department from April 2005 to Oct 2008.Results The diagnosis of insulinoma of these 4 patients was made by Whipple's triad,hypoglycemia and high serum insulin.Tumor localization studies showed:only one patient of 4 ultrasonography had positive finding,none had positive finding though CT(5.0 mm).After underwent intraarterial calcium stimuliation and venous sampling(ASVS)test,all patients underwent CT(2.5 mm+enhance)to localization.All patients had been localizated.3 cases with insulinoma were proved by surgery and pathology,1 case refused surgery.The localization of tumor by ASVS test and CT(2.5 mm+enhance)was confirmed in surgery in all 3 cases.Conclusion The diagnosis of insulinoma is made by Whipple's triad,hypoglycemia and high serum insulin.ASVS test and CT(2.5 mm+enhance)are safe and accurate studies in insulinoma localization,they can increase insulinoma preoperative localization.
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Objective To evaluate the diagnosis of insulinoma and tumor localization in 4 cases.Methods There were 4 patients diagnosed as insulinoma in our department from April 2005 to Oct 2008.Results The diagnosis of insulinoma of these 4 patients was made by Whipple's triad,hypoglycemia and high serum insulin.Tumor localization studies showed:only one patient of 4 ultrasonography had positive finding,none had positive finding though CT(5.0 mm).After underwent intraarterial calcium stimuliation and venous sampling(ASVS)test,all patients underwent CT(2.5 mm+enhance)to localization.All patients had been localizated.3 cases with insulinoma were proved by surgery and pathology,1 case refused surgery.The localization of tumor by ASVS test and CT(2.5 mm+enhance)was confirmed in surgery in all 3 cases.Conclusion The diagnosis of insulinoma is made by Whipple's triad,hypoglycemia and high serum insulin.ASVS test and CT(2.5 mm+enhance)are safe and accurate studies in insulinoma localization,they can increase insulinoma preoperative localization.
Key concepts: Insulinoma, Medicine, Hypoglycemia, Radiology, Whipple Procedure, Insulin, Pancreas, Internal medicine