Discussion of the value of the application of blood culture,the serum procalcitonin and high sensitivity creactive protein in neonatal sepsis patients

Objective To evaluate the clinical significance of the detection of blood culture,serum procalcitonin(PCT) and high sensitivity C-reactive protein(hs-CRP) in the diagnosis of neonatal sepsis.Methods Solid-phase immune chromatography and immune nephelometry were used to determine the levels of serum PCT and CRP in neo-natal sepsis patients,and the test was data compared with the results of blood culture.Results The levels of PCT and CRP in the neonatal sepsis group were significantly higher than those in the controls(P0.01) .However,the levels of PCT compared with the results of blood culture in the neonatal sepsis group were not significant(P0.05) ,while the levels of hs-CRP,compared with the results of blood culture in the same group,were significant(P0.01) . Conclusion Both PCT and CRP are the important makers for early diagnosis of neonatal sepsis,and can make the im-portant supplement experiment of the blood culture.