Comparison of Clinical Effect Between MPCNL and PCNL in the Treatment for Renal Calculi

Objective:To compare the outcomes of the surgical treatment of renal calculi with minimally invasive percutaneous nephrolithotomy (MPCNL) and percutaneous nephrolithotomy (PCNL). Methods:A total of 125 patients with renal calculi were assigned to undergo either MPCNL or PCNL surgery. Clinical data including operation time,stone-free rate,and complications were compared. Results:16F and 22F percutaneous renal access were successfully established in MPCNL and PCNL group respectively. The MPCNL group had a longer operation time than the PCNL group. One-stage stone-free rate for simple renal pelvis stone was significantly lower in the MPCNL group than in the PCNL group. However,the rate for multiple stones was significantly higher in the MPCNL group than in the PCNL group (P0.05). There was no statistical difference in the one-stage stone-free rate for staghorn stone between the two groups (P0.05). One patients in MPCNL group and three patients in PCNL group had blood transfusion intraoperatively or postoperatively,while 10 and 5 patients respectively in the two groups had postoperative fever (both P0.05). Pre-and post-operation serum creatinine and blood urea nitrogen level in patients with renal insufficiency was not statistical different between the two groups respectively. And there was no statistically difference in the cases of renal function improvement,stability,and deterioration between the two groups. Conclusion:Standard tract PCNL had the same security as MPCNL in the treatment of kidney stones. The two operative methods had low incidence of complications and could preserve renal function efficaciously. Standard tract PCNL would significantly reduce the operation-time and may be suitable for large renal stone,while MPCNL may has advantages in the treatment for small renal pelvis stone and renal calyx stone.