Recovery degree of regional wall motion abnormalities in hibernating myocardium of coronary heart disease after complete revascularization

Objective: This study was designed to evaluate the recovery degree of regional wall motion abnormalities (RWMA) in hibernating myocardium of coronary heart disease (CHD) after complete revascularization. Methods: Twenty-three patients (16 male, 7 female, age at 61±9 years) with hibernating but without infarcted myocardium were included in this study. There were 14, 9 cases with lesion in LAD, RCA respecrively, complicated with stenosis of 95. 2±4.1% and TIMI flow of 2. 1±0. 7 degrees. Complete revascularization was achieved by PTCA plus stenting. Wall motion abnormalities score (WMAS) by echocardiography was employed to assess the change of regional myocardial function after 6 months. Results: In the segments with mild-moderate and severe RWMA, WMAS was 6. 9±3. 5 and 13. 9±4. 4 respectively before revascularization, and become 0. 6±0. 4 and 2. 9±2. 1 respectively after revascularization (P0. 01). In regions supplying by LAD and RCA, WMAS was 14. 2 ±4. 3 and 7. 0±3. 2 respectively before revascularization, and become 3. 1±2. 0 and 0. 4±0. 5 respectively after revascularization (P 0. 01). Conclusion:Recovery of regional wall motion abnormalities can be significantly ameliorated,but can't complete recovery by complete revascularization in hibernating myocardium of CHD.