2012•Chinese Journal of Health Laboratory TechnologyRequires access

Analysis of etiological surveillance of hand,foot and mouth disease during 2010-2011 in Qujing

Yan Fan

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Abstract

Objective:To analyze the etiological characteristics of hand,foot and mouth disease(HFMD) in Qujing from 2010 to 2011,and provide basis for further control and prevention.Methods:Feces,throat-swab specimens and fluid from blisters were collected from patients with HFMD in different medical institutions,and the enterovirus nuclear acid detection and typing identification were done by real-time RT-PCR.Results:235 specimens were tested positive for enterovirus from 284 specimens,the total positive rate was 82.75% from May 2010 to Dec.2011.In all cases,116 samples(49.36%) were EV71 type and 119 samples(50.64%) were CoxA16.Mostcases(92.96%) were children under 5 years old.Enterovirus positive rate(90.67%) in feces was higher than that in fluid from blisters which was 88.89%.Conclusion:The major causative pathogens for HFMD in Qujing were CoxA16 in 2010 and EV71 in 2011.Children under 5 years old were high risk population.EV71 was the pre-dominant type which led to serious conditions.

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Objective:To analyze the etiological characteristics of hand,foot and mouth disease(HFMD) in Qujing from 2010 to 2011,and provide basis for further control and prevention.Methods:Feces,throat-swab specimens and fluid from blisters were collected from patients with HFMD in different medical institutions,and the enterovirus nuclear acid detection and typing identification were done by real-time RT-PCR.Results:235 specimens were tested positive for enterovirus from 284 specimens,the total positive rate was 82.75% from May 2010 to Dec.2011.In all cases,116 samples(49.36%) were EV71 type and 119 samples(50.64%) were CoxA16.Mostcases(92.96%) were children under 5 years old.Enterovirus positive rate(90.67%) in feces was higher than that in fluid from blisters which was 88.89%.Conclusion:The major causative pathogens for HFMD in Qujing were CoxA16 in 2010 and EV71 in 2011.Children under 5 years old were high risk population.EV71 was the pre-dominant type which led to serious conditions.

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Available abstract

Objective:To analyze the etiological characteristics of hand,foot and mouth disease(HFMD) in Qujing from 2010 to 2011,and provide basis for further control and prevention.Methods:Feces,throat-swab specimens and fluid from blisters were collected from patients with HFMD in different medical institutions,and the enterovirus nuclear acid detection and typing identification were done by real-time RT-PCR.Results:235 specimens were tested positive for enterovirus from 284 specimens,the total positive rate was 82.75% from May 2010 to Dec.2011.In all cases,116 samples(49.36%) were EV71 type and 119 samples(50.64%) were CoxA16.Mostcases(92.96%) were children under 5 years old.Enterovirus positive rate(90.67%) in feces was higher than that in fluid from blisters which was 88.89%.Conclusion:The major causative pathogens for HFMD in Qujing were CoxA16 in 2010 and EV71 in 2011.Children under 5 years old were high risk population.EV71 was the pre-dominant type which led to serious conditions.

Key concepts: Etiology, Hand-foot-and-mouth disease, Enterovirus, Feces, Throat, Medicine, Population, Typing

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