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Zymographic Analysis of MMP in Human Lung Adenocarcinoma Cell Lines with Differential Metastatic Potential

Chenghui Yan, Wu Yan, Jin Yan, Songbin Fu

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Abstract

To investigate the relationship between the MMP activities and metastatic ability in human lung adenocarcinoma cell lines with differential metastatic potential.Nine lung adenocarcinoma cell lines were tested for their MMP activities by zymographic analysis methods.The MMP production capabilities of carcinoma cells rose following the increase of their metastatic potentials.The result suggested that there was some relationship between MMP－9 activties and metastatic potential in human lung adenocarcinomas.

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What this paper is about

To investigate the relationship between the MMP activities and metastatic ability in human lung adenocarcinoma cell lines with differential metastatic potential.Nine lung adenocarcinoma cell lines were tested for their MMP activities by zymographic analysis methods.The MMP production capabilities of carcinoma cells rose following the increase of their metastatic potentials.The result suggested that there was some relationship between MMP－9 activties and metastatic potential in human lung adenocarcinomas.

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Available abstract

To investigate the relationship between the MMP activities and metastatic ability in human lung adenocarcinoma cell lines with differential metastatic potential.Nine lung adenocarcinoma cell lines were tested for their MMP activities by zymographic analysis methods.The MMP production capabilities of carcinoma cells rose following the increase of their metastatic potentials.The result suggested that there was some relationship between MMP－9 activties and metastatic potential in human lung adenocarcinomas.

Key concepts: Adenocarcinoma, Biology, Cell culture, Matrix metalloproteinase, Lung, Cancer research, Differential diagnosis, Metastasis

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Zymographic Analysis of MMP in Human Lung Adenocarcinoma Cell Lines with Differential Metastatic Potential — Research Paper | ScholarLens