2008Zhongguo xiandai yixue/Zhongguo xiandai yixue zazhiRequires access

Application of Remifentanil by TCI without relaxant for tracheal intubation in pediatric patients

Chengxiang Yang

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Abstract

[Objective] To observe the tracheal intubation conditions hemodynamic changes during Remifentanil target controlled infusion(TCI) at different plasma concentrations combined with Propofol. [Methods] Forty-five pediatric patients were randomly allocated into three groups. Remifentanil were given using TCI at plasma concentration of 2 ng/mL,3 ng/mL and 4 ng/mL in each group respectively and after 5-min Remifentanil infusion, Propofol was given with TCI at plasma concentration 2.5 μg/mL. Ten minutes later, inserting laryngoscope and tracheal intubation were teied and intubation conditions were recorded. If failed, the Remifentanil concentration was tried ten minutes later. The heart rate and blood pressure at baseline, after Remifentanil infusion, before intubation and one minute after intubation were recorded.Meanwhile, the intubation scores and side effects during induction were recorded.

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What this paper is about

[Objective] To observe the tracheal intubation conditions hemodynamic changes during Remifentanil target controlled infusion(TCI) at different plasma concentrations combined with Propofol. [Methods] Forty-five pediatric patients were randomly allocated into three groups. Remifentanil were given using TCI at plasma concentration of 2 ng/mL,3 ng/mL and 4 ng/mL in each group respectively and after 5-min Remifentanil infusion, Propofol was given with TCI at plasma concentration 2.5 μg/mL. Ten minutes later, inserting laryngoscope and tracheal intubation were teied and intubation conditions were recorded. If failed, the Remifentanil concentration was tried ten minutes later. The heart rate and blood pressure at baseline, after Remifentanil infusion, before intubation and one minute after intubation were recorded.Meanwhile, the intubation scores and side effects during induction were recorded.

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Available abstract

[Objective] To observe the tracheal intubation conditions hemodynamic changes during Remifentanil target controlled infusion(TCI) at different plasma concentrations combined with Propofol. [Methods] Forty-five pediatric patients were randomly allocated into three groups. Remifentanil were given using TCI at plasma concentration of 2 ng/mL,3 ng/mL and 4 ng/mL in each group respectively and after 5-min Remifentanil infusion, Propofol was given with TCI at plasma concentration 2.5 μg/mL. Ten minutes later, inserting laryngoscope and tracheal intubation were teied and intubation conditions were recorded. If failed, the Remifentanil concentration was tried ten minutes later. The heart rate and blood pressure at baseline, after Remifentanil infusion, before intubation and one minute after intubation were recorded.Meanwhile, the intubation scores and side effects during induction were recorded.

Key concepts: Remifentanil, Intubation, Anesthesia, Medicine, Propofol, Tracheal intubation, Heart rate, Plasma concentration

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