Rescue percutaneous coronary intervention for failed thrombolisisin in acute myocardial infarction

Objective To evaluate the safety and efficiency of the rescue angioplasty following thrombolttic therapy in acute myocardial infarction(AMI). Methods Among the patients within 12 hours from the onset of symptoms of AMI,58cases (subgroup A)underwent primary coronary angioplasty and 64 cases(subgroup B) underwent intravenous thrombolitic therapy. According to clinical early reperfusion indication within 90 minutes following thrombolic therapy,group B was divided two subgroups,the patients with early reperfution (subgroup C)underwent delayed interventional examination 7-10 days after AMI and that with non-reperfution (subgroup D)underwent rescue angioplasty the reperfution rates and complications in different groups were analyzed and compared.Cardiac function(left ventricular ejection fraction,LVEF)was evaluated by echocardiograph 1month after AMI. Results The results showed that the rate of reperfusion,in group A is 94.7%(36/38),that of subgroup D was 95.5%(42/44)within 90 minutes following thrombolic therapy. There were no serious complications that occurred in subgroup C and D, The LVEFs in group A,subgroupC and D were not significantly different,but there was a significant difference between referfusion within 12 hours and beyond after AMI (63.2% vs 51.3%,P0.05). Conclusion The resue angioplasty following failed thrombolic therapy is safe and efficient.