Clinical research of application of different types of anesthesia in laparoscopic cholecystectomy

Objective:To compare PETCO2 and hemodynamic change in laparoscopic cholecystectomy(LC) under general anesthesia and general-epidural combined anesthesia.Methods:40 patients of LC were divided into general anesthesia group(A group,n=20) and general-thoracic epidural anesthesia group(B group,n=20) randomly.All patients’SBP,DBP,MAP,HR,ECG,SpO2,BIS and PetCO2 were monitored continuously.To record SBP,DBP,MAP,HR,PetCO2 before anesthesia,after tracheal intubation,at 10min,20min after pneumoperitoneum and at 10min after the removal of pneumoperitoneum,extubation time and drug consumption of fentanyl and propofolwere observed.Results:After tracheal intubation,at 10min,20min after pneumoperitoneum and at 10min after the removal of pneu-moperitoneum,SBP,DBP,MAP in group A increased significantly than those in group B(P0.05).During pneumoperitoneum,HR wereincreased significantly in group A(P0.05).On the contrary,there was no change in group B(P0.05),at 20min after pneumoperitoneumPetCO2 was increased significantly between group A and group B,especially group A(P0.05),there was difference between two groups(P0.05).The time of extubation was shorter comparatively in group B(P0.05).Conclusion:The respiration and hemodynamic changesare slighter during LC under general-thoracic epidural anesthesia than general anesthesia,furthermore,the recovery quality is better.Anesthetists should strengthen the detection of PetCO2,especially after the removal of pneumoperitoneum.