Treatment of post traumatic acute respiratory distress syndrome using pressure controlled ventilation

Objective:To study the therapeutic effects of pressure controlled ventilation on posttraumatic acute respiratory distress syndrome(ARDS).Methods:Eighteen patients with posttraumatic ARDS were included in the study.The patients received mechanical ventilation immediately after admission and were randomly divided into two groups:pressure controlled ventilation (PCV) group (n=8) and volume controlled ventilation (VCV) group (n=10).Peak airway pressure (PIP),mean airway pressure (MPaw) and positive endexpiratory pressure(PEEP) at 6 hour (PTh6) and 12 hour (PTh12) after treatment in the two groups were recorded and compared.Blood gas analysis,blood pressure,heart and respiratory rates were compared before and after PCV treatment.Results:PIP in PCV group at PTh6 and PTh12 were (2 24±0 12)kPa (1 kPa=10 20 cmH 2O) and (1 98±0 08)kPa,respectively,and were significantly lower than those in the VCV group (both P0 01).The MPaw and PEEP in PCV group at PTh6 were (1 12 ±0 09)kPa and (0 79±0 12)kPa,respectively,and showed no significant difference with those in the VCV group (both P0 05).But the two parameters at PTh12 in PCV group,which were (0 85±0 08) kPa and (0 55±0 04) kPa respectively,were significantly lower than those in the VCV group (P0 05 and P0 01).The blood gas analysis,heart and respiratory rates were obviously improved in PCV treatment group,and no significant changes in blood pressure was observed.Conclusions:PCV can significantly lower the PIP level with no disturbance to MPaw,PEEP and hemodynamics.It is useful in the treatment of posttraumatic ARDS.