2013•Xiandai shengwu yixue jinzhanRequires access
Application of Brain Natriuretic Peptide in Diagnosis and Treatment of Chronic Heart Failure
Lipin Chen
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Abstract
Objective: To analyze the value of NT-pro BNP in diagnosis and treatment of chronic heart failure. Methods: 82 cases of patients with heart failure were selected in our hospital from March 2012 to March 2013 as the experimental group, while another 80healthy people as a control group. Then we analyzed brain natriuretic peptide concentration in the experimental group and a control group,and brain natriuretic peptide concentration changes after patients of the experimental group were treated, all staff were given echocardiography and then observed the relationship between the experimental group brain natriuretic peptide concentration and left ventricular ejection fraction and cardiac function. Results: Brain natriuretic peptide concentration of patients in experimental group was significantly higher than the control group, the difference was statistically significant(P 0.05); significant changes in brain natriuretic peptide concentration in the experimental group before and after treatment, the difference was statistically significant(P 0.05); cardiac function and left ventricular ejection fraction between the different classification of brain natriuretic peptide concentration, at all levels of the difference was statistically significant(P 0.05); brain natriuretic peptide concentration reference value determination of the sensitivity and specificity. Conclusion: Brain natriuretic peptide has an important meaning in the diagnosis and treatment of chronic heart failure.