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Expression of p73 gene in human non-small cell lung cancer in vitro

Zhi Li

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Abstract

Objective To study the expression of p73 in human non small cell lung cancer (NSCLC) and the relationship between p73 expression and clinico pathological parameters. Methods Expression of p73 gene was detected by RT PCR in 32 human NSCLC tissues, tissues adjacent to cancer and non cancer lung tissues. Results p73 gene expression up regulated substantially and detected in 87.5%(28/32) of human NSCLC tissues while expressed at low level in tissues adjacent to cancer and non cancer lung tissues. Conclusion Marked up regulation of p73 gene expression is found in human NSCLC.

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What this paper is about

Objective To study the expression of p73 in human non small cell lung cancer (NSCLC) and the relationship between p73 expression and clinico pathological parameters. Methods Expression of p73 gene was detected by RT PCR in 32 human NSCLC tissues, tissues adjacent to cancer and non cancer lung tissues. Results p73 gene expression up regulated substantially and detected in 87.5%(28/32) of human NSCLC tissues while expressed at low level in tissues adjacent to cancer and non cancer lung tissues. Conclusion Marked up regulation of p73 gene expression is found in human NSCLC.

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Available abstract

Objective To study the expression of p73 in human non small cell lung cancer (NSCLC) and the relationship between p73 expression and clinico pathological parameters. Methods Expression of p73 gene was detected by RT PCR in 32 human NSCLC tissues, tissues adjacent to cancer and non cancer lung tissues. Results p73 gene expression up regulated substantially and detected in 87.5%(28/32) of human NSCLC tissues while expressed at low level in tissues adjacent to cancer and non cancer lung tissues. Conclusion Marked up regulation of p73 gene expression is found in human NSCLC.

Key concepts: Lung cancer, Gene, Gene expression, Cancer research, Biology, Cancer, In vitro, Cell

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