Effects of epidural Sufentanil infusions used for ankle fracture patients postoperative analgesia

Objective To observe the effects of epidural Sufentanil infusion in different dosage used for postoperative analgesia in ankle fracture patients.Methods All of 120 patients fo ASAⅠ-Ⅱ ankle fracture surgery patients under epidural block anesthesia were randomly divided into three groups(n = 40,each group): GroupⅠreceived sufentanil 0.03 μg(kg·h)for postoperative analgesia through ambulatory epidural analgesia(PCEA);groupⅡreceived sufentanil 0.45 μg/(kg·h) and group Ⅲ received sufentanil 0.06 μg(kg·h),each group was compatibility of medicines with 0.178% Ropivacaine Mesylate injection.Visual analogue score,epidural analgesia pump's service condition,whether to use other analgesic drugs and side effects were recorded at the end of operation.Results Analgesic score(VAS score) at 6、12、24 and 48 hour after operation、times of press the pump and use of assist analgesic drugs within 48 hours in groupⅡor Ⅲ were below groupⅠ's(P 0.05).The incidence of nausea and vomiting in GroupⅠorⅡcompared with group Ⅲ had statistically significant difference(P 0.05).Each group of respiratory inhibition and itching were gradually increasing incidence,but between two groups was no statistically significant(P 0.05).Conclusion Sufentanil 0.45 μg/(kg·h) and 0.178% Ropivacaine Mesylate injection can be used for PCEA in ankle fracture patient's postoperative analgesia with better effects and less side effects.