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The risk factors for ventilator-associated pneumonia in patients undergoing craniotomy

Tang Wen-ji

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Abstract

Objective To explore the risk factors for ventilator-associated pneumonia(VAP) in patients undergoing craniotomy.Methods The data of one hundred forty-nine patients on mechanical ventilation after craniotomy were collected.18 possible risk factors for VAP were examined by univariate analysis and then by multivariate logistic regression analysis.Results Of 149 patients,94 developed VAP.Multivariate logistic regression analysis indicated that prior antibiotic use,duration of mechanical ventilation ≥ 6 days,antacid use for ≥ 5 days,and length of ICU stay ≥ 7 days were the independent risk factors for VAP.Conclusions VAP is induced by multiple factors.A comprehensive measure should be taken to control the occurrence of VAP.

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What this paper is about

Objective To explore the risk factors for ventilator-associated pneumonia(VAP) in patients undergoing craniotomy.Methods The data of one hundred forty-nine patients on mechanical ventilation after craniotomy were collected.18 possible risk factors for VAP were examined by univariate analysis and then by multivariate logistic regression analysis.Results Of 149 patients,94 developed VAP.Multivariate logistic regression analysis indicated that prior antibiotic use,duration of mechanical ventilation ≥ 6 days,antacid use for ≥ 5 days,and length of ICU stay ≥ 7 days were the independent risk factors for VAP.Conclusions VAP is induced by multiple factors.A comprehensive measure should be taken to control the occurrence of VAP.

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Available abstract

Objective To explore the risk factors for ventilator-associated pneumonia(VAP) in patients undergoing craniotomy.Methods The data of one hundred forty-nine patients on mechanical ventilation after craniotomy were collected.18 possible risk factors for VAP were examined by univariate analysis and then by multivariate logistic regression analysis.Results Of 149 patients,94 developed VAP.Multivariate logistic regression analysis indicated that prior antibiotic use,duration of mechanical ventilation ≥ 6 days,antacid use for ≥ 5 days,and length of ICU stay ≥ 7 days were the independent risk factors for VAP.Conclusions VAP is induced by multiple factors.A comprehensive measure should be taken to control the occurrence of VAP.

Key concepts: Medicine, Ventilator-associated pneumonia, Logistic regression, Mechanical ventilation, Pneumonia, Craniotomy, Univariate analysis, Multivariate analysis

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