Hemodynamic changes during propofol,sevoflurane anesthesia in the elderly patients undergoing lapsroscopic surgery

Objective To evaluate the effect of propofol/remifentanil,sevoflurane/remifentanil on cardiovascular system in the elderly patients undergoing lapsroscopic surgery.Methods Fifty ASA Ⅰ or Ⅱpatients aged ≥60y undergoing elective laparoscopic cholecystectomy were randomly divided into two groups:propofol group(n=25,group P)and sevoflurane group(n=25,group S).After rapid induction all patients were intubated with a tube.Anesthesia was maintained with continuous infusion of propofol 0.1 mg·kg-1·min-1 and remifentanil 1 μg·kg-1·min-1 in group P,3%-4% end-tidal concentration of sevoflurane and remifentanil 1 μg·kg-1·min-1 in group S.Hemodynamic variables including cardiac output(CO),cardiac index(CI)and systemic vascular resistance(SVR)were continuously measured through-out anesthesia.Results The hemodynamic status of all patients was little influenced by any one of two anesthesia techniques in P group or in S group at clinical dosages.Conclusion In ASAⅠ or Ⅱ elderly patients undergoing lapsroscopic surgery propofol affects CO,CI and SVR in a similar degree to sevoflurane.[