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2009•Zhongguo shengwuzhipinxue zazhiRequires access

Application of Recombinant Adeno-Associated Virus in Gene Therapy

Shenrong Jing

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Abstract

Recombinant adeno-associated virus(rAAV)has good safety and low immunogenicity,which may infect both di-vided and undivided cells and mediate the long-term and stable gene expression.As a gene delivery system,rAAV is paid more and more attentions in study on gene therapy.The application of rAAV in gene therapy is reviewed in this paper.

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What this paper is about

Recombinant adeno-associated virus(rAAV)has good safety and low immunogenicity,which may infect both di-vided and undivided cells and mediate the long-term and stable gene expression.As a gene delivery system,rAAV is paid more and more attentions in study on gene therapy.The application of rAAV in gene therapy is reviewed in this paper.

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Available abstract

Recombinant adeno-associated virus(rAAV)has good safety and low immunogenicity,which may infect both di-vided and undivided cells and mediate the long-term and stable gene expression.As a gene delivery system,rAAV is paid more and more attentions in study on gene therapy.The application of rAAV in gene therapy is reviewed in this paper.

Key concepts: Adeno-associated virus, Genetic enhancement, Recombinant DNA, Immunogenicity, Virology, Gene delivery, Gene, Recombinant virus

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