Analysis on clinical drug resistance of multi-drug resistant Mycobacterium tuberculosis

Objective To investigate the drug resitance in inpatients with tuberculosis from Guiyang pulmonary hospital,and provide reliable reference on the clinical diagnosis and treatment of multi-drug resistant tuberculosis(MDR-TB).Methods From January 2004 to August 2009,the types of clinical isolates from the hospital were identified.The drug resistance in the patients with different kinds of tuberculosis was analyzed by drug sensitive test.Results The multi-drug resistance rate of 2 318 Mycobacterium tuberculosis was 23.8%.The initial multi-drug resistance rate was 12.1%,and the acquired multi-drug resistance rate was 63.8%.Conclusions The drug resistance rate in the patients with tuberculosis in Guiyang pulmonary hospital is high.The drug resistant tuberculosis should be prevented and controlled as soon as possible,in order to reduce the number of patients with MDR-TB.