Expression of KAI1/CD82 in Mouse Endometrium during Early Pregnancy

Objective To fuarther explore the similarity between embryo implantation and tumor metastasis.Methods We use RT-PCR and immunohistochemistry to detect the expression of KAI1/CD82 mRNA and protein in mice endometrium during days 1-8 of pregnancy.Result In early pregnant uterus,the expression of KAI1/CD82 mRNA increased gradually and,coupled with the increased level and range of the protein expression.Conclusion The expression of KAI1/CD82 mRNA and its protein were under dynanmic changes in mice uterus during early pregnacy period,which indicate that KAI1/CD82 maybe one of the modulating factors in controlling the accurate invasion of embryo into endometrium.