Quantitative assessment of left ventricular diastolic function in patients with dilated cardiomyopathy by using three-dimensional echocardiography

Objective To evaluate the feasibility of three-dimensional echocardiography(3DE) for quantitative assessment of left ventricular diastolic function(LVDF) in patients with dilated cardiomyopathy(DCM).Methods Thirty patients with DCM(DCM group) and 30 normal subjects(control group) underwent echocardiography.The end-diastolic volume(EDV),end-systolic volume(ESV),stroke volume(SV) and ejection fraction(EF) were measured with 3DE,and the one-third diastolic filling fraction(1/3FF) was calculated.Correlation between 1/3FF and E/E' was analyzed.Results EDV,ESV,SV and E/E' in DCM group were higher than those in control group(all P0.05),while EF and 1/3FF in DCM group were lower than those in control group(both P0.05).There was significantly negative correlation between 1/3FF and E/E' in both groups(both r=-0.81,both P0.05).Conclusion 3DE can quantitatively evaluate LVDF of DCM patients,and can be used as a new method for clinical evaluation of LVDF.