Pathogen Changes and Antibiotics Use in Urinary Tract Infectionfor Children: A Clinical Analysis

OBJECTIVE To learn the changes in pathogenic bacteria and the uses of antibiotics in urinary tract infection for children. METHODS The clinical data of 38 cases of children with urinary tract infections were analyzed retrospectively. All of the isolates were tested by Kirby-Bauer susceptibility method, and the antibiotic resistance was judged according to NCCLS standard. RESULTS Gram-negative bacilli were the most common pathogens, the majority was Escherichia coli occupied 42.1%, the rate of Gram-positive cocci which was 26.3% went up. The multiple drug resistances of bacteria were seen in the most isolates to the commonly used antibiotics, showing drug-resistance to ampicillin with related data. Cefoperazone/sulbactam, amikacin, vancomycin and imipenem were the most sensitive drugs presently. CONCLUSIONS Much attention should be paid to drug resistance detection in the treatment of urinary tract infections, and the antibiotics must be selected according to the results of susceptibility tests.