Curative Effect of the Combined Treatment with Sulfasalazine and Medilac-S for Ulcerative Colitis

Objective To evaluate the curative effect of the combined treatment with Sulfasalazine and Medilac-S for ulcerative colitis. Methods 47 cases with light or moderate ulcerative colitis at active stage were randomly divided into 2 groups: treatment group(n=24),receiving Sulfasalazine and Medilac-S and control group(n=23),receiving Sulfasalazine only;the curative effect,the reoccurrence in 6 months,the change of main symptoms before and after treatment and the drug adverse reaction were evaluated.Results The total effective rate of treatment group(95.83%) was significantly higher than that of control group(78.26%)(P0.05);there existed an obvious difference in symptom relief,such as abdominal pain,diarrhea,mucus bloody stool and tenesmus,between the 2 groups after treatment(P0.05);the adverse reaction in treatment group was slight.Conclusions the combined treatment with Sulfasalazine and Medilac-S is of better curative effect for ulcerative colitis and it can reduce the reoccurrence.