Clinical analysis of 18 cases of neurosyphilis

Objective To improve knowledge of neurosyphilis,reduce misdiagnosis,provide early treatment and reduce complications based on discussion of its early clinical manifestations,atypical clinical manifestations,serum,cerebrospinal fluid and imaging characteristics.Methods Retrospective analysis was applied on the clinical data of 18 patients confirmed with neurosyphilis and given inpatient care in our hospital from March 2010 to January 2013.Results 18 cases of neurosyphilis were given routine treatment and received follow-up visits for 6 months.8 cases were cured and 10 cases were improved.Conclusion Misdiagnosis and missed diagnosis might occur due to diverse and complex clinical manifestations of neurosyphilis.Treatment with enough penicillin dosage through the course of treatment is critical for prognosis.It is recommended to conduct routine screening of serum syphilis antibodies on patients suspected with intracranial infection,cognitive dysfunction,mental disorders and unexplained cerebral infarction.