2008•Unpublished venueRequires access

Analysis of distribution of nosocomial fungal infection in tumor patients and their antibiotic resistance

Huang Jin-lian

Abstract

Objective:To investigate the fungal pathogens and drug resistance in tumor patients with fungal infection.Methods:A total of 863 patients data were collected from tumor patients with fungal infection.Their resistance to anti-fungal agents were analyzead.Results:The incidence of fungal infection was 14.02%(121/863)among all the samples.Candida albicans was the major fungus and accounted for 69.4%(84/121).Resistance rates of fungus against econazole(ECO) and ketoconazole(KET)were 34.7% and 29.0%,resitstance rates to miconazole(MIC),amphotericin B(AMB),nystain(NYS)and 5-flucytosine(5-FC) were 20.0%,3.3%,1.65% and 1.65%.Conclusion:The main pathogens causing fungal infection in tumor patients is candida albicans.The results of antifungal susceptibility test can guide the clinical antifungal therapy.

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Key concepts: Miconazole, Ketoconazole, Econazole, Candida albicans, Flucytosine, Amphotericin B, Microbiology, Drug resistance