Related factors for hepatocirrhosis with spontaneous bacterial peritonitis and treatment countermeasures

OBJECTIVE To study and analyze the relevant factors for the spontaneous bacterial peritonitis combined with hepatocirrhosis,so as to provide bases for better treatment.METHODS A retrospective analysis of 64 hepatocirrhosis patients with liver cirrhosis spontaneous bacterial peritonitis was performed,and 46 cases of patients with liver cirrhosis spontaneous bacterial peritonitis were set as control,the statistical analysis of the general data,original diseases,liver meritorious service,and liver function and the classifications of the two groups were compared,the results of ascites bacteriological culture,treatment and the mortality of the study group were analyzed.RESULTS The ratio of the men and women in the study group was 3.9∶1,1.6∶1 in the control group,the difference was statistically significant(P0.05);the difference in the age was not statistically significant;among the primary diseases of the two groups,hepatitis B liver cirrhosis was the majority,as compared with other original diseases,the difference in the hepatitis B liver cirrhosis between the two groups was statistically significant(P0.05);there was statistical significance in ALT of the two groups;but the differences in the TBIL,ALB and the classification of liver function between the two groups were statistically significant(P0.05);of 68 strains of pathogens cultured from ascites,Escherichia coli was the majority,followed by Klebsiella pneumoniae;the effective rate of the treatment in the study group was 65.6%,the mortality rate in the study group was 21.9%,19.6% in the control group,the difference in the mortality rate between the two groups was not statistically significant.CONCLUSION Hepatocirrhosis combined with liver cirrhosis spontaneous bacterial peritonitis is closely related to the gender,hepatitis combined with primary diseases,liver function and its classification,E.coli is the major pathogen isolated from ascites,it is necessary to use sensitive antibiotics on the basis of the protection of liver,adding albumin,and symptomatic treatment,which can ensure the clinical efficacy