2014•China Medicine and PharmacyRequires access

Effect of preoperativeelective transcatheter arterial chemoembolization on surgical effect of patients with hepatic carcinoma

MA Chenshen

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Abstract

Objective To explore the effect of preoperative transcatheter arterial chemoembolization( TACE) on life quality and prognosis of patients with hepatocellular carcinoma receiving hepatectomy. Methods Data of 130 patients with hepatic cancer were analyzed retrospectively. 65 patients received preoperative TACE( TACE group), and 65 patients did not receive preoperative TACE( control group). Changes of relapse rate and survival rate in 1, 2, 3 years after the surgery were compared, and the effect of preoperative TACE for resectable hepatic cancer was evaluated. Results There was no difference of 1-year and 3-year relapse rate between the two groups. 2-year relapse rate in the TACE group was 31.2%, significantly lower than that of 59.2% in the control group( P 0.05); 3-year survival rate in the TACE group was 54.1%, significantly higher than that of 32.3% in the control group( P 0.05). Conclusion Preoperative elective TACE for resectable hepatic cancer under strict conditions, to some extent, can improve the curative effect of the surgery.

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Objective To explore the effect of preoperative transcatheter arterial chemoembolization( TACE) on life quality and prognosis of patients with hepatocellular carcinoma receiving hepatectomy. Methods Data of 130 patients with hepatic cancer were analyzed retrospectively. 65 patients received preoperative TACE( TACE group), and 65 patients did not receive preoperative TACE( control group). Changes of relapse rate and survival rate in 1, 2, 3 years after the surgery were compared, and the effect of preoperative TACE for resectable hepatic cancer was evaluated. Results There was no difference of 1-year and 3-year relapse rate between the two groups. 2-year relapse rate in the TACE group was 31.2%, significantly lower than that of 59.2% in the control group( P 0.05); 3-year survival rate in the TACE group was 54.1%, significantly higher than that of 32.3% in the control group( P 0.05). Conclusion Preoperative elective TACE for resectable hepatic cancer under strict conditions, to some extent, can improve the curative effect of the surgery.

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Available abstract

Objective To explore the effect of preoperative transcatheter arterial chemoembolization( TACE) on life quality and prognosis of patients with hepatocellular carcinoma receiving hepatectomy. Methods Data of 130 patients with hepatic cancer were analyzed retrospectively. 65 patients received preoperative TACE( TACE group), and 65 patients did not receive preoperative TACE( control group). Changes of relapse rate and survival rate in 1, 2, 3 years after the surgery were compared, and the effect of preoperative TACE for resectable hepatic cancer was evaluated. Results There was no difference of 1-year and 3-year relapse rate between the two groups. 2-year relapse rate in the TACE group was 31.2%, significantly lower than that of 59.2% in the control group( P 0.05); 3-year survival rate in the TACE group was 54.1%, significantly higher than that of 32.3% in the control group( P 0.05). Conclusion Preoperative elective TACE for resectable hepatic cancer under strict conditions, to some extent, can improve the curative effect of the surgery.

Key concepts: Medicine, Transcatheter arterial chemoembolization, Hepatocellular carcinoma, Hepatectomy, Survival rate, Surgery, Gastroenterology, Internal medicine

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