2012•Journal of Henan University of Science & TechnologyRequires access

Clinical Significance of Serum Procalcition in Treatment of Acute Exacerbations of Chronic Obstructive Pulmonary

Xiaoyan Liu

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Abstract

Objective This article aims to explore serum calcitonin original for chronic obstructive pulmonary disease(AECOPD) in patients with acute aggravating period antibiotic application significance. Methods 60 cases of acute exacerbation of chronic obstructive pulmonary disease were randomly divided into the PCT steering group and the control group,PCT steering group when PCT0.15 μg/L deactivated with or without use antibiotics,the conventional therapy group according to the result of laboratory,clinical experience decided to the use of antimicrobials,observe two groups of the use of antibacterial drugs in time,cost and length of hospital stay. Results The serum procalcitonin group antibiotic use days(P=0.005),antibiotic use(P=0.023),antibiotic costs(P=0.001),total costs(P=0.006) was significantly less than the control group,the two groups had significant difference(P0.05). Conclusion PCT can be used to guide the AECOPD patients of antibiotics use and disable timing,and patients can effectively reduce the use of antibiotics in time and costs,while reducing hospitalization time.

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Objective This article aims to explore serum calcitonin original for chronic obstructive pulmonary disease(AECOPD) in patients with acute aggravating period antibiotic application significance. Methods 60 cases of acute exacerbation of chronic obstructive pulmonary disease were randomly divided into the PCT steering group and the control group,PCT steering group when PCT0.15 μg/L deactivated with or without use antibiotics,the conventional therapy group according to the result of laboratory,clinical experience decided to the use of antimicrobials,observe two groups of the use of antibacterial drugs in time,cost and length of hospital stay. Results The serum procalcitonin group antibiotic use days(P=0.005),antibiotic use(P=0.023),antibiotic costs(P=0.001),total costs(P=0.006) was significantly less than the control group,the two groups had significant difference(P0.05). Conclusion PCT can be used to guide the AECOPD patients of antibiotics use and disable timing,and patients can effectively reduce the use of antibiotics in time and costs,while reducing hospitalization time.

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Available abstract

Objective This article aims to explore serum calcitonin original for chronic obstructive pulmonary disease(AECOPD) in patients with acute aggravating period antibiotic application significance. Methods 60 cases of acute exacerbation of chronic obstructive pulmonary disease were randomly divided into the PCT steering group and the control group,PCT steering group when PCT0.15 μg/L deactivated with or without use antibiotics,the conventional therapy group according to the result of laboratory,clinical experience decided to the use of antimicrobials,observe two groups of the use of antibacterial drugs in time,cost and length of hospital stay. Results The serum procalcitonin group antibiotic use days(P=0.005),antibiotic use(P=0.023),antibiotic costs(P=0.001),total costs(P=0.006) was significantly less than the control group,the two groups had significant difference(P0.05). Conclusion PCT can be used to guide the AECOPD patients of antibiotics use and disable timing,and patients can effectively reduce the use of antibiotics in time and costs,while reducing hospitalization time.

Key concepts: Medicine, Procalcitonin, Antibiotics, Pulmonary disease, Acute exacerbation of chronic obstructive pulmonary disease, Exacerbation, COPD, Internal medicine

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