[Measurement of central corneal thickness in myopic eyes with ultrasound and Pentacam scheimpflug system].

OBJECTIVE: To assess the accuracy and variability of central corneal thickness measurements in myopic eyes obtained by ultrasound pachymetry and the Pentacam scheimpflug imaging system. METHODS: First, corneal thickness in 50 healthy eyes was measured three times with the Pentacam system to evaluate the repeatability. Then, Scheimpflug imaging system (Pentacam) and A-scan ultrasonic pachymeter (SP-3000) were used to measure the corneal thickness on 217 myopic cases (433 eyes) undergoing laser in situ keratomileusis (LASIK) and 63 cases (126 eyes) 6 months after LASIK. The results were compared. RESULTS: Repeated-measures ANOVA showed the repeatability of the Pentacam measurements was high (P > 0.05). Pre-operatively, the value of corneal central thickness measured by ultrasonic pachymetry and the Pentacam system was (537.26 +/- 31.61) microm and (538.08 +/- 32.72) microm, respectively. There was no significant difference between the results of these two methods (t = 1.867, P > 0.05). The difference between these two methods ranged -35 - 34 microm, and was within -20 - 20 microm in 95.38% cases. Post-operatively, the value of corneal central thickness measured by ultrasonic pachymetry and the Pentacam system was (464.21 +/- 41.04) microm and (465.17 +/- 42.65) microm, respectively. There was no significant difference between these two methods, too (t = 0.913, P > 0.05). There was a significant linear correlation between the two methods (P < 0.001). The thinnest point of cornea was mostly located surrounding the apex and inclined towards inferotemporal. CONCLUSION: The Pentacam scheimpflug system offers an acceptable method for evaluating corneal pachymetry, which is useful in corneal refractive surgery.