2010•Xiandai shengwu yixue jinzhanRequires access
Establishment of HSV-1 Infected Cell Culture System
Liang Yi, Youkun Lin, Ming Liang
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Abstract
Objective:To establish a stable HSV-1 infected cell culture system,in order to provide a stable platform for further basic and clinical research of skin disease caused by HSV-1 .Methods:HSV-1 strains were propagated in vero cells and hep-2 cells were served as targets of HSV-1 infection.Then cytopathic effect (CPE) was performed and observed.Results:Abundance of HSV-1 were stable propagated in Vero cells;The CPE occurred obviously in hep-2 cells after infected by HSV-1.Conclusion:The HSV-1 infected cell culture system we established was stable for utilization,in which HSV-1 strains were propagated in vero cells and hep-2 cells were served as targets of HSV-1 infection.The system could be used as a stable platform for further basic and clinical research of skin disease caused by HSV-1.