ScholarLens Back to search
2004•Chinese Clinical OncologyRequires access

Clinical study on vinorelbine plus oxaliplatin in advanced non-small-cell lung cancer

Zhang Yi-pin

Open publisher page 0 citations

Abstract

Objective:To study the efficiency and t oxicity of vinorelbine plus oxaliplatin chemotherapy in treatment of advanced no n-small-cell lung cancer.Methods:Vinorelbine was administered on days 1 and 8,wi th dose of 25 mg/m 2. Oxaliplatin was given at the dose of 130 mg/m 2 on da y 2. Treatment was repeated every 3 weeks.Results:There are twenty-five patients. A total of 81 c ycles were given,for a median of three per patient (range 2～6). There are 9 partial response,giving an objective response rate of 36%. The median overall survival was 8 months and 1-year survival rate was 20%. The major toxicities were myelosuppression,nausea/vomiting,phlebitis.Conclusion:The vinorelbine-oxaliplatin doublet regimen i s a safe and active combined chemotherapy.

About this research paper

What this paper is about

Objective:To study the efficiency and t oxicity of vinorelbine plus oxaliplatin chemotherapy in treatment of advanced no n-small-cell lung cancer.Methods:Vinorelbine was administered on days 1 and 8,wi th dose of 25 mg/m 2. Oxaliplatin was given at the dose of 130 mg/m 2 on da y 2. Treatment was repeated every 3 weeks.Results:There are twenty-five patients. A total of 81 c ycles were given,for a median of three per patient (range 2～6). There are 9 partial response,giving an objective response rate of 36%. The median overall survival was 8 months and 1-year survival rate was 20%. The major toxicities were myelosuppression,nausea/vomiting,phlebitis.Conclusion:The vinorelbine-oxaliplatin doublet regimen i s a safe and active combined chemotherapy.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To study the efficiency and t oxicity of vinorelbine plus oxaliplatin chemotherapy in treatment of advanced no n-small-cell lung cancer.Methods:Vinorelbine was administered on days 1 and 8,wi th dose of 25 mg/m 2. Oxaliplatin was given at the dose of 130 mg/m 2 on da y 2. Treatment was repeated every 3 weeks.Results:There are twenty-five patients. A total of 81 c ycles were given,for a median of three per patient (range 2～6). There are 9 partial response,giving an objective response rate of 36%. The median overall survival was 8 months and 1-year survival rate was 20%. The major toxicities were myelosuppression,nausea/vomiting,phlebitis.Conclusion:The vinorelbine-oxaliplatin doublet regimen i s a safe and active combined chemotherapy.

Key concepts: Vinorelbine, Oxaliplatin, Medicine, Nausea, Regimen, Lung cancer, Chemotherapy, Vomiting

Back to paper searchBrowse research topicsOriginal source
Clinical study on vinorelbine plus oxaliplatin in advanced non-small-cell lung cancer — Research Paper | ScholarLens