Q FEVER: A CONTINUING DIAGNOSTIC PROBLEM IN WEST TEXAS AND EASTERN NEW MEXICO.
Sharmila Sehli, Marc T.M. Shaw, Robert C. Kimbrough, Maisha Robinson, Cynthia Jumper
Abstract
Sharmila Sehli, Marc T.M. Shaw, Robert C. Kimbrough, Maisha Robinson, Cynthia Jumper
Abstract
Background Q fever is a widespread zoonotic infection caused by the pathogen Coxiella burnetii that has both acute and chronic manifestations. Q fever may present as a fever of unknown origin (FUO). We examined three cases of Q fever in west Texas and eastern New Mexico: two chronic and one acute that presented as FUO. Q fever usually occurs following exposure to infected animals. Q fever continues to be a diagnostic possibility in patients with FUO and animal exposure in the southwestern United States. Methods Cases review from medical records at our institution 2000-2006. Results: Discussion Q fever may present as an acute or chronic febrile illness, either of which can have nonspecific symptoms and signs. Serologic studies are necessary for the diagnosis. Phase I and phase II serology will differentiate between acute and chronic disease. Although somewhat slow and costly, these studies are key to appropriate diagnosis and therapy. Conclusion Q fever continues to be a diagnostic problem in west Texas and eastern New Mexico.
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Background Q fever is a widespread zoonotic infection caused by the pathogen Coxiella burnetii that has both acute and chronic manifestations. Q fever may present as a fever of unknown origin (FUO). We examined three cases of Q fever in west Texas and eastern New Mexico: two chronic and one acute that presented as FUO. Q fever usually occurs following exposure to infected animals. Q fever continues to be a diagnostic possibility in patients with FUO and animal exposure in the southwestern United States. Methods Cases review from medical records at our institution 2000-2006. Results: Discussion Q fever may present as an acute or chronic febrile illness, either of which can have nonspecific symptoms and signs. Serologic studies are necessary for the diagnosis. Phase I and phase II serology will differentiate between acute and chronic disease. Although somewhat slow and costly, these studies are key to appropriate diagnosis and therapy. Conclusion Q fever continues to be a diagnostic problem in west Texas and eastern New Mexico.
Key concepts: Q fever, Coxiella burnetii, Fever of unknown origin, Serology, Medicine, Immunology, Pediatrics, Intensive care medicine