Comparative study of cyclopentolate 1% and atropine 1% in retinoscopic refraction for Chinese hyperopic children.

Objective To compare cycloplegic retinoscopic refractions using cyclopentolate 1% and atropine 1% in Chinese hyperopic children of 3 to 7 year old.Methods Cyclopentolate 1% was used for cycloplegic retinoscopy on 3 to 7 years old children from the outpatient clinic,and 1 week later,atropine 1% was used for cycloplegic retinoscopy on children who had a cycloplegic refraction larger than +0.75D.50 children(90 eyes) were enrolled in this study.Refraction was presented as spherical equivalent(SE),and paired sample t test and χ2 test were used to analyze the data.Results(1)The SE of retinoscopy for cyclopentolate 1% and atropine 1% was +3.67±2.39D and +4.52±2.49D,respectively(P0.001);(2)in esotropic children,the SE of retinoscopy for cyclopentolate 1% and atropine 1% was +3.95±2.30D and +4.91±2.51D,respectively(P0.001);in children without esotropia,the SE of retinoscopy for cyclopentolate 1% and atropine 1% was +3.32±2.49D and +4.03±2.41D,respectively(P0.001);the SE difference between cyclopentolate 1% and atropine 1% in esotropic and non-esotropic children was +0.97±0.75D and +0.70±0.40D,respectively(P0.001);(3)in 55 eyes with SE difference ≤0.75D and 35 eyes with SE difference 0.75D,the number of eyes with cyclopentolate 1% SE ≥+3D and +3D had no statistical difference(P=0.562).Conclusion In 3 to 7 year old Chinese hyperopic children,especially esotropic children,atropine 1% is the choice of drug in cycloplegic retinoscopy.