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TNF Inhibitors for Rheumatoid Arthritis

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Abstract

Two inhibitors of tumor necrosis factor (TNF) -- etanercept (Enbrel), which binds to TNF, and infliximab (Remicade), a monoclonal antibody against TNF -- now are available for treatment of rheumatoid arthritis (RA). Findings from 2 large trials, funded by the drugs' manufacturers, add to the existing data. In one study, 632 patients with early …

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What this paper is about

Two inhibitors of tumor necrosis factor (TNF) -- etanercept (Enbrel), which binds to TNF, and infliximab (Remicade), a monoclonal antibody against TNF -- now are available for treatment of rheumatoid arthritis (RA). Findings from 2 large trials, funded by the drugs' manufacturers, add to the existing data. In one study, 632 patients with early …

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OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Two inhibitors of tumor necrosis factor (TNF) -- etanercept (Enbrel), which binds to TNF, and infliximab (Remicade), a monoclonal antibody against TNF -- now are available for treatment of rheumatoid arthritis (RA). Findings from 2 large trials, funded by the drugs' manufacturers, add to the existing data. In one study, 632 patients with early …

Key concepts: Etanercept, Rheumatoid arthritis, Infliximab, Medicine, Tumor necrosis factor alpha, Monoclonal antibody, TNF inhibitor, Tumor necrosis factor α

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