2016The Egyptian Journal of OtolaryngologyOpen access

Intermediate-grade mucoepidermoid carcinoma arising from Warthin’s tumour of parotid gland

Arsheed Hussain Hakeem, Imtiyaz Hussain Hakeem, Fozia Jeelani Wani

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Abstract

Warthin’s tumour (WT), also known as the adenolymphoma, is the second common benign neoplasm that mostly occurs in the parotid gland. Malignant transformation of the epithelial or lymphoid component of the WT has been rarely reported. We describe a case of a 73-year-old woman who underwent total radical parotidectomy with modified neck dissection on the left side. The case was diagnosed as intermediate-grade mucoepidermoid carcinoma developed in the setting of WT based on histomorphologic findings. Clinical presentation, pathogenesis, differential diagnosis and management of the rare malignancy have been discussed briefly.

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What this paper is about

Warthin’s tumour (WT), also known as the adenolymphoma, is the second common benign neoplasm that mostly occurs in the parotid gland. Malignant transformation of the epithelial or lymphoid component of the WT has been rarely reported. We describe a case of a 73-year-old woman who underwent total radical parotidectomy with modified neck dissection on the left side. The case was diagnosed as intermediate-grade mucoepidermoid carcinoma developed in the setting of WT based on histomorphologic findings. Clinical presentation, pathogenesis, differential diagnosis and management of the rare malignancy have been discussed briefly.

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Available abstract

Warthin’s tumour (WT), also known as the adenolymphoma, is the second common benign neoplasm that mostly occurs in the parotid gland. Malignant transformation of the epithelial or lymphoid component of the WT has been rarely reported. We describe a case of a 73-year-old woman who underwent total radical parotidectomy with modified neck dissection on the left side. The case was diagnosed as intermediate-grade mucoepidermoid carcinoma developed in the setting of WT based on histomorphologic findings. Clinical presentation, pathogenesis, differential diagnosis and management of the rare malignancy have been discussed briefly.

Key concepts: Mucoepidermoid carcinoma, Medicine, Adenolymphoma, Parotid gland, Neck dissection, Malignancy, Parotidectomy, Pathology

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