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Has the Role of Acute HIV Infection in Overall HIV Transmission Been Overestimated

Keith Henry

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Abstract

Estimates of the contribution of acute HIV infection to overall HIV transmissions vary from 50%. Many such estimates were based on data from the retrospective Rakai cohort (serodiscordant heterosexual couples in Uganda involved in a study evaluating HIV transmission risk), with the most commonly quoted increased risk for transmission during acute infection ranging from 30 to 70 excess-hazard …

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What this paper is about

Estimates of the contribution of acute HIV infection to overall HIV transmissions vary from 50%. Many such estimates were based on data from the retrospective Rakai cohort (serodiscordant heterosexual couples in Uganda involved in a study evaluating HIV transmission risk), with the most commonly quoted increased risk for transmission during acute infection ranging from 30 to 70 excess-hazard …

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Available abstract

Estimates of the contribution of acute HIV infection to overall HIV transmissions vary from 50%. Many such estimates were based on data from the retrospective Rakai cohort (serodiscordant heterosexual couples in Uganda involved in a study evaluating HIV transmission risk), with the most commonly quoted increased risk for transmission during acute infection ranging from 30 to 70 excess-hazard …

Key concepts: Serodiscordant, Medicine, Human immunodeficiency virus (HIV), Transmission (telecommunications), Cohort, Retrospective cohort study, Cohort study, Virology

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