A new ACRS-SNP in the 5’ flanking region of the bovine insulin-like growth factor 1 (IGF1) gene (Brief report)

Abstract. A number of polymorphisms within the bovine insulin-like growth factor 1 (IGF1) gene were described at this time. One of these mutations, a low polymorphic (CA)n microsatellite in the 5’ flanking region of the gene, has been reported by KIRKPATRICK (1992). A T>C transition was identified in the P1 promoter region of the bovine IGF1K gene (GenBank Acc. No. AF017143; GE et al., 2001). LIEN et al. (2000) identified a 4-bp deletion (TTTG) and nine point mutations within non-coding regions of the gene (GenBank Acc. No. AF210383-387). In our study, the sequencing of (CA)n microsatellite fragment revealed another single nucleotide polymorphism (SNP) in the 5’ flanking region of the bovine IGF1 gene. The DNA sequence has been deposited to GenBank under accession number DQ975234.