1974•PubMedRequires access

Cloxacillin-resistant Staphylococcus aureus in a children's hospital.

WG Davis, CE White

Abstract

A group of cultures of cloxacillin-resistant Staphylococcus aureus was collected over a period of 6 months. The method of determination of resistance to cloxacillin is described. The use of the disc diffusion test for cloxacillin was found to be unsatisfactory. The incidence of cloxacillin-resistant Staph. aureus at the Red Cross War Memorial Children's Hospital (inpatients as well as outpatients) is slightly less than 2% of all isolates of Staph. aureus . Of the total non-White ward patients with penicillin-resistant Staph. aureus infections, 6,5% have staphylococci resistant to cloxacillin. Reaction of these isolates to Fucidin, c1indamycin and erythromycin is described. S. Afr. Med. J ., 48, 1341 (1974).

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Key concepts: Cloxacillin, Medicine, Staphylococcus aureus, Penicillin, Erythromycin, Staphylococcal infections, Incidence (geometry), Microbiology