[Management of severe sepsis and septic shock].
Antoine Cuche, Paul Rutz, Lionel Trueb
Abstract
Antoine Cuche, Paul Rutz, Lionel Trueb
Abstract
Severe sepsis and septic shock are systemic manifestations of the host response to infection. Mortality remains high despite advances in pathophysiological knowledge. Hemodynamic and respiratory management is largely supportive, while early antibiotics administration and source of infection's control are crucial for patient outcome. We review the principles guiding the initial management of these patients in emergency situation.
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Severe sepsis and septic shock are systemic manifestations of the host response to infection. Mortality remains high despite advances in pathophysiological knowledge. Hemodynamic and respiratory management is largely supportive, while early antibiotics administration and source of infection's control are crucial for patient outcome. We review the principles guiding the initial management of these patients in emergency situation.
Key concepts: Septic shock, Sepsis, Intensive care medicine, Medicine, Shock (circulatory), Pathophysiology, Antibiotics, Severe sepsis