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Induction of 2',5'oligo (A) synthetase in animals bearing Ehrlich ascites tumor cells.

Grammati Galaktidou, A. Kortsaris, Athanassios Papageorgiou, S I Koliais

Abstract

The activity of 2',5'oligo(A) synthetase in experimental mice inoculated with poly(I) poly(C) is higher in the animals with transplantable tumors (Ehrlich Ascites Tumor cells) compared to animals without the tumor. The higher enzymatic activity is detected in tissue homogenates from liver and spleen, as well as in homogenates from the Ascites cells.

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Key concepts: Ascites, Ehrlich ascites, Spleen, Enzyme, Tumor cells, Neoplasm, Biology, Ratón