Additional sedative drugs to light sedation with dexmedetomidine is risk for delirium

Light sedation is preferred for critical ill patients. We often use dexmedetomidine for light sedation, but sometimes additional sedative drugs(such as midazolam and propofol) is needed. Benzodiazepine is risk for delirium, but it is unclear benzodiazepine use combined with dexmedetomidine is risk for delirium.