Monitoring of Clinical Distribution and Drug Resistance in Acinetobacter baumannii Strains in Hubei Province

OBJECTIVE To monitor the distribution and antimicrobial resistance of clinical isolates of Acinetobacter baumannii(ABA)strains from the sixteen hospitals in Hubei Province from 2005 to 2006.METHODS A total of 1546 clinical isolates of ABA strains were collected.Sample′s source,department distribution and detection rate were investigated.The K-B methods were adopted to detect 14 antibiotics′ susceptibility.Drug sensitivity results were analyzed by WHONET5.3.RESULTS Samples were mainly from sputum(76.7%);the most of department distribution was medical department(34.2%).Cefoperazone/sulbactam showed the lowest drug resistance(15.7%),followed by imipenem(18.0%) and meropenem(31.7%).The drug resistance rate of the remaining 11 antibiotics were all between 53.3% and 79.8%.Altogether 263 imipenem resistant strains and 6 pan-drug resistant strains were detected.CONCLUSION The monitoring to the drug resistance of A.baumannii should be strengthened to prevent the outbreak of its nosocomial infection.