Acute generalised exanthematous pustulosis and toxic epidermal necrolysis induced by carbamazepine Goh T K, Pang S M, Thirumoorthy T, Goh S G N
Goh Teck Kheng, Simei St
Abstract
Goh Teck Kheng, Simei St
Abstract
Acute generalised exanthematous pustulosis and Stevens-Johnson syndrome (toxic epidermal necrolysis spectrum of severe cutaneous drug reactions) are believed to have distinct underlying pathophysiologies. Our patient, a 28-year-old Chinese woman, represents the first known reported case of clinically-consistent and histologically-proven acute generalised exanthematous pustulosis and toxic epidermal necrolysis overlap induced by carbamazepine in the English literature.
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Acute generalised exanthematous pustulosis and Stevens-Johnson syndrome (toxic epidermal necrolysis spectrum of severe cutaneous drug reactions) are believed to have distinct underlying pathophysiologies. Our patient, a 28-year-old Chinese woman, represents the first known reported case of clinically-consistent and histologically-proven acute generalised exanthematous pustulosis and toxic epidermal necrolysis overlap induced by carbamazepine in the English literature.
Key concepts: Toxic epidermal necrolysis, Acute generalized exanthematous pustulosis, Dermatology, Carbamazepine, Pustulosis, Medicine, Drug reaction, Drug