2008Unpublished venueRequires access

Acute generalised exanthematous pustulosis and toxic epidermal necrolysis induced by carbamazepine Goh T K, Pang S M, Thirumoorthy T, Goh S G N

Goh Teck Kheng, Simei St

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Abstract

Acute generalised exanthematous pustulosis and Stevens-Johnson syndrome (toxic epidermal necrolysis spectrum of severe cutaneous drug reactions) are believed to have distinct underlying pathophysiologies. Our patient, a 28-year-old Chinese woman, represents the first known reported case of clinically-consistent and histologically-proven acute generalised exanthematous pustulosis and toxic epidermal necrolysis overlap induced by carbamazepine in the English literature.

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What this paper is about

Acute generalised exanthematous pustulosis and Stevens-Johnson syndrome (toxic epidermal necrolysis spectrum of severe cutaneous drug reactions) are believed to have distinct underlying pathophysiologies. Our patient, a 28-year-old Chinese woman, represents the first known reported case of clinically-consistent and histologically-proven acute generalised exanthematous pustulosis and toxic epidermal necrolysis overlap induced by carbamazepine in the English literature.

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Available abstract

Acute generalised exanthematous pustulosis and Stevens-Johnson syndrome (toxic epidermal necrolysis spectrum of severe cutaneous drug reactions) are believed to have distinct underlying pathophysiologies. Our patient, a 28-year-old Chinese woman, represents the first known reported case of clinically-consistent and histologically-proven acute generalised exanthematous pustulosis and toxic epidermal necrolysis overlap induced by carbamazepine in the English literature.

Key concepts: Toxic epidermal necrolysis, Acute generalized exanthematous pustulosis, Dermatology, Carbamazepine, Pustulosis, Medicine, Drug reaction, Drug

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Acute generalised exanthematous pustulosis and toxic epidermal necrolysis induced by carbamazepine Goh T K, Pang S M, Thirumoorthy T, Goh S G N — Research Paper | ScholarLens