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1958•New England Journal of MedicineRequires access

Splenectomy in Hemolytic Anemia

Paul R. McCurdy, Charles E. Rath, Kenneth McCoy

Open publisher page 47 citations

Abstract

SPLENECTOMY has been employed for many years in the treatment of hemolytic anemia. Although striking improvement can be expected in certain types of hemolytic anemia — particularly hereditary spherocytosis — results of splenectomy in other types have generally been unpredictable. The observations of Jandl et al.1 on body-surface scanning after the injection of red cells tagged with radioactive chromate (Cr51) suggested that this technic might be helpful in predicting the results of splenectomy.The present report is concerned with the evaluation of this procedure in 50 patients, including 10 in whom splenectomy was done.Material and MethodsPatients were . . .

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What this paper is about

SPLENECTOMY has been employed for many years in the treatment of hemolytic anemia. Although striking improvement can be expected in certain types of hemolytic anemia — particularly hereditary spherocytosis — results of splenectomy in other types have generally been unpredictable. The observations of Jandl et al.1 on body-surface scanning after the injection of red cells tagged with radioactive chromate (Cr51) suggested that this technic might be helpful in predicting the results of splenectomy.The present report is concerned with the evaluation of this procedure in 50 patients, including 10 in whom splenectomy was done.Material and MethodsPatients were . . .

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OpenAlex reports 47 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

SPLENECTOMY has been employed for many years in the treatment of hemolytic anemia. Although striking improvement can be expected in certain types of hemolytic anemia — particularly hereditary spherocytosis — results of splenectomy in other types have generally been unpredictable. The observations of Jandl et al.1 on body-surface scanning after the injection of red cells tagged with radioactive chromate (Cr51) suggested that this technic might be helpful in predicting the results of splenectomy.The present report is concerned with the evaluation of this procedure in 50 patients, including 10 in whom splenectomy was done.Material and MethodsPatients were . . .

Key concepts: Splenectomy, Medicine, Hereditary spherocytosis, Hemolytic anemia, Spherocytosis, Anemia, Autoimmune hemolytic anemia, Hemolysis

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