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Aqueous Sublingual Allergen Immunotherapy Looks Promising

David J. Amrol

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Abstract

Sublingual immunotherapy (SLIT) can be administered using tablets, aqueous allergen extracts, or microencapsulated preparations. SLIT is used widely in Europe, and U.S. clinicians are beginning to prescribe off-label aqueous SLIT preparations. The most promising U.S. studies have involved grass tablets; aqueous preparations have yielded varying results. In an industry-sponsored U.S. trial, researchers randomized 381 adults with ragweed allergies to sublingual allergen …

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What this paper is about

Sublingual immunotherapy (SLIT) can be administered using tablets, aqueous allergen extracts, or microencapsulated preparations. SLIT is used widely in Europe, and U.S. clinicians are beginning to prescribe off-label aqueous SLIT preparations. The most promising U.S. studies have involved grass tablets; aqueous preparations have yielded varying results. In an industry-sponsored U.S. trial, researchers randomized 381 adults with ragweed allergies to sublingual allergen …

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Available abstract

Sublingual immunotherapy (SLIT) can be administered using tablets, aqueous allergen extracts, or microencapsulated preparations. SLIT is used widely in Europe, and U.S. clinicians are beginning to prescribe off-label aqueous SLIT preparations. The most promising U.S. studies have involved grass tablets; aqueous preparations have yielded varying results. In an industry-sponsored U.S. trial, researchers randomized 381 adults with ragweed allergies to sublingual allergen …

Key concepts: Sublingual immunotherapy, Ragweed, Slit, Medicine, Allergen, Allergy, Allergen immunotherapy, Aqueous solution

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