Articles Tumoral calcinosis: radiologic-pathologic correlation

Objective. Tumoral calcinosis is a frequently misdiagnosed disorder. This study details the radiologic and pathologic characteristics of tumoral calcinosis that distinguish it from most other entities. Design. Radiologic and pathologic findings, and medical records of 12 patients with tumoral calcinosis were re- viewed and compared with equivalent information about 5 patients with other calcified lesions. Patients. The 12 patients ranged in age from 15 months to 62 years. Six had idiopathic tumoral calcinosis and 6 had secondary tumoral calcinosis. Results and conclusions. A consistent radiologic finding for tumoral calcinosis was a dense calcified mass that was homogeneous except for a chicken wire pattern of lucencies, which correlated histologically with thin fi- brous septae. Other characteristics of tumoral calcinosis included fluid-calcium levels, demonstrated in four pa- tients, and smooth osseous erosions adjacent to the mass, demonstrated in three patients. Five cases of tumoral cal- cinosis were originally confused with other calcified le- sions; however, the radiologic findings were characteris- tic of tumoral calcinosis in retrospect.