1999•Japanese Journal of Oral & Maxillofacial SurgeryOpen access

Malignant acanthosis nigricans and Leser-Trelat sign with oral papillomatosis: Report of a case.

Akira SATO, Tsuyoshi Iihama, Fumio Ito, Syuji TOYA, Akira Tanaka, Izumi Mataga

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Abstract

Acantosis nigricans is an uncommon dermatologic disorder with papillary proliferation, pigmentation, and hyperkeratosis that is associated with malignant tumors in internal organs. We report on an elderly patient who had malignant acantosis nigricans associated with oral florid papillomatosis and Leser-Trélat sign. Advanced gastric cancer was found after detecting oral papillomatosis and dermal symptoms in this patient.

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Acantosis nigricans is an uncommon dermatologic disorder with papillary proliferation, pigmentation, and hyperkeratosis that is associated with malignant tumors in internal organs. We report on an elderly patient who had malignant acantosis nigricans associated with oral florid papillomatosis and Leser-Trélat sign. Advanced gastric cancer was found after detecting oral papillomatosis and dermal symptoms in this patient.

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Available abstract

Acantosis nigricans is an uncommon dermatologic disorder with papillary proliferation, pigmentation, and hyperkeratosis that is associated with malignant tumors in internal organs. We report on an elderly patient who had malignant acantosis nigricans associated with oral florid papillomatosis and Leser-Trélat sign. Advanced gastric cancer was found after detecting oral papillomatosis and dermal symptoms in this patient.

Key concepts: Papillomatosis, Acanthosis nigricans, Medicine, Dermatology, Hyperkeratosis, Keratosis, Sign (mathematics), Papilloma

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Malignant acanthosis nigricans and Leser-Trelat sign with oral papillomatosis: Report of a case. — Research Paper | ScholarLens