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Specificity of Enhanced Immunological Sensitization of Mice Following Injections of Antigens and Specific Antisera.

Geronimo Terres, Richard D. Stoner

Open publisher page 27 citations

Abstract

An enhanced antibody response to bovine serum albumin and fluid tetanus toxoid was found in mice when these antigens were injected in slight antigen excess with specific heterologous antisera. The specificity of the enhanced response was limited to specific antigens in complex. An enhanced response was also demonstrated to rabbit gamma globulin by testing the capacity of passively immunized mice to degrade I131-labeled RGG at an accelerated rate.

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What this paper is about

An enhanced antibody response to bovine serum albumin and fluid tetanus toxoid was found in mice when these antigens were injected in slight antigen excess with specific heterologous antisera. The specificity of the enhanced response was limited to specific antigens in complex. An enhanced response was also demonstrated to rabbit gamma globulin by testing the capacity of passively immunized mice to degrade I131-labeled RGG at an accelerated rate.

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Available abstract

An enhanced antibody response to bovine serum albumin and fluid tetanus toxoid was found in mice when these antigens were injected in slight antigen excess with specific heterologous antisera. The specificity of the enhanced response was limited to specific antigens in complex. An enhanced response was also demonstrated to rabbit gamma globulin by testing the capacity of passively immunized mice to degrade I131-labeled RGG at an accelerated rate.

Key concepts: Heterologous, Antiserum, Toxoid, Antigen, Sensitization, Immunology, Antibody, Gamma globulin

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Specificity of Enhanced Immunological Sensitization of Mice Following Injections of Antigens and Specific Antisera. — Research Paper | ScholarLens