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1949•New England Journal of MedicineRequires access

Hepatitis without Jaundice and without Hepatomegaly

T. J. Domenici

Open publisher page 9 citations

Abstract

FOUR cases of hepatitis without jaundice and without hepatomegaly constitute the material of this report. Hepatitis without jaundice has been variously described as a "mild disease"1 and "mild non-icteric form of hepatitis,"2 running a course of six to eight weeks. A review of the literature reveals that an enlarged and tender liver is an essential finding in virus hepatitis and in the hepatitis seen in infectious mononucleosis. The cases presented below were severe illnesses running a four to six months' course. The liver was not enlarged, but instead a sharply circumscribed area of localized tenderness in the right upper quadrant . . .

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What this paper is about

FOUR cases of hepatitis without jaundice and without hepatomegaly constitute the material of this report. Hepatitis without jaundice has been variously described as a "mild disease"1 and "mild non-icteric form of hepatitis,"2 running a course of six to eight weeks. A review of the literature reveals that an enlarged and tender liver is an essential finding in virus hepatitis and in the hepatitis seen in infectious mononucleosis. The cases presented below were severe illnesses running a four to six months' course. The liver was not enlarged, but instead a sharply circumscribed area of localized tenderness in the right upper quadrant . . .

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OpenAlex reports 9 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

FOUR cases of hepatitis without jaundice and without hepatomegaly constitute the material of this report. Hepatitis without jaundice has been variously described as a "mild disease"1 and "mild non-icteric form of hepatitis,"2 running a course of six to eight weeks. A review of the literature reveals that an enlarged and tender liver is an essential finding in virus hepatitis and in the hepatitis seen in infectious mononucleosis. The cases presented below were severe illnesses running a four to six months' course. The liver was not enlarged, but instead a sharply circumscribed area of localized tenderness in the right upper quadrant . . .

Key concepts: Jaundice, Medicine, Mononucleosis, Hepatitis, Hepatitis A, Liver disease, Viral hepatitis, Quadrant (abdomen)

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