2014•IOSR Journal of Pharmacy and Biological SciencesOpen access

Morphological changes in liver, kidney tissues of animals' exposure to lead acetate

Sahar H. Abdul Kareem

Abstract

The study was carried out to evaluate changes induced by lead acetate toxicity in 20 wistar rats which were divided into 3 different groups I, II and III.Animals of group I received singlnormal saline only as a control group.G II received one injection intraperitoneally of lead acetate (8 mg) only, while group III received lead acetate and herbs extract of Cyprus esculentus (drinking with water for period of 4 weeks).Rats were sacrificed on 15th and 30 days of treatment and tissues obtained for histological evaluation included liver, kidney, and heart .Liver tissue showed changes ,necrosis with depleasion in the glycoprotein granules inside the hepatocyte cells , there is no changes in kidney and heart tissue .

Open-access reader

About this research paper

What this paper is about

Why it matters

OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Lead acetate, Lead exposure, Kidney, Lead (geology), Anatomy, Biology, Chemistry, Pathology