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Tenecteplase Is More Effective with Enoxaparin than with Unfractionated Heparin

James M. Christenson, Frcpc

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Abstract

The optimal pharmacologic regimen for patients with ST-elevation myocardial infarction (STEMI) is under debate. The GUSTO-V trial failed to demonstrate that the addition of abciximab to reteplase reduced mortality, whereas the ASSENT-3 trial demonstrated a reduction in combined death, MI, and recurrent ischemia when either abciximab or enoxaparin …

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What this paper is about

The optimal pharmacologic regimen for patients with ST-elevation myocardial infarction (STEMI) is under debate. The GUSTO-V trial failed to demonstrate that the addition of abciximab to reteplase reduced mortality, whereas the ASSENT-3 trial demonstrated a reduction in combined death, MI, and recurrent ischemia when either abciximab or enoxaparin …

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Available abstract

The optimal pharmacologic regimen for patients with ST-elevation myocardial infarction (STEMI) is under debate. The GUSTO-V trial failed to demonstrate that the addition of abciximab to reteplase reduced mortality, whereas the ASSENT-3 trial demonstrated a reduction in combined death, MI, and recurrent ischemia when either abciximab or enoxaparin …

Key concepts: Reteplase, Tenecteplase, Abciximab, Medicine, Myocardial infarction, Heparin, Internal medicine, Cardiology

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Tenecteplase Is More Effective with Enoxaparin than with Unfractionated Heparin — Research Paper | ScholarLens