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1983•American Journal of Clinical PathologyRequires access

Central Nervous System Involvement as a Presenting Feature of Acute Monocytic Leukemia: Preceding Leukemia by 12 Months.

James E. Hamous, Linda E. Ansbacher, Jamés O. Armitage

Open publisher page 9 citations

Abstract

This report describes a patient who presented with a diffuse malignant central nervous system (CNS) process composed of cells with monocytic differentiation one year before the development of acute monocytic leukemia. A similar presentation has been documented for acute lymphocytic leukemia, but to the best of our knowledge, this is the first report to detail a diffuse CNS malignancy as the presenting symptom for acute monocytic leukemia.

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What this paper is about

This report describes a patient who presented with a diffuse malignant central nervous system (CNS) process composed of cells with monocytic differentiation one year before the development of acute monocytic leukemia. A similar presentation has been documented for acute lymphocytic leukemia, but to the best of our knowledge, this is the first report to detail a diffuse CNS malignancy as the presenting symptom for acute monocytic leukemia.

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OpenAlex reports 9 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

This report describes a patient who presented with a diffuse malignant central nervous system (CNS) process composed of cells with monocytic differentiation one year before the development of acute monocytic leukemia. A similar presentation has been documented for acute lymphocytic leukemia, but to the best of our knowledge, this is the first report to detail a diffuse CNS malignancy as the presenting symptom for acute monocytic leukemia.

Key concepts: Acute monocytic leukemia, Monocytic leukemia, THP1 cell line, Leukemia, Acute leukemia, Malignancy, Medicine, Central nervous system

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Central Nervous System Involvement as a Presenting Feature of Acute Monocytic Leukemia: Preceding Leukemia by 12 Months. — Research Paper | ScholarLens